Nutrition Support in Pancreatitis: Beyond Parenteral Nutrition
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چکیده
19 INTRODUCTION P ancreatitis is caused by activation of pancreatic digestive enzymes within the pancreas leading to pain and inflammation (1). The inflammatory response to pancreatitis is similar to that of sepsis and can precipitate systemic inflammatory response syndrome (SIRS). SIRS can lead to multiple system organ failure, sepsis, hypermetabolism, hypercatabolism, and increased mortality in severe cases (2,3,4,5). The integrity of the gastrointestinal tract may also be affected by SIRS by increasing the intestinal permeability and altering the normal gut barrier with resultant bacterial translocation potential (2,3,6,7,8). Seventy to eighty percent of hospitalizations due to pancreatitis are mild cases resolving in 5–7 days with only conventional therapy that includes fluid resuscitation, pain management, antibiotic therapy, and withholding oral intake to avoid pain exacerbation (3,9,10,11). Nutrition Support in Pancreatitis: Beyond Parenteral Nutrition NUTRITION SUPPORT IN GASTROENTEROLOGY, SERIES #1
منابع مشابه
Nutrition in patients with acute pancreatitis.
Acute pancreatitis is a disease with varying severity. Patients with the mild form do not require nutritional support because oral intake is resumed rapidly. Studies on nutritional support in acute pancreatitis have included patients with both mild and severe disease. In this heterogeneous group, total parenteral nutrition did not improve outcome compared with no nutrition at all. This is cause...
متن کاملGuidelines for specialized nutritional and metabolic support in the critically-ill patient: update. Consensus SEMICYUC-SENPE: severe acute pancreatitis.
Severe acute pancreatitis (SAP) causes local and systemic complications leading to high catabolic, hypermetabolic and hyperdynamic stress states with marked morbidity and mortality. In the last decade, nutritional support has become a key element in the treatment of SAP. Thus, specialized nutrition is indicated from admission, with enteral nutrition being preferred to parenteral nutrition. Ente...
متن کاملMeta-analysis: total parenteral nutrition versus total enteral nutrition in predicted severe acute pancreatitis.
BACKGROUND Total parenteral nutrition (TPN) as a traditional mode of treatment in severe acute pancreatitis was still used widely in clinical work. In addition, enteral nutrition treatment methods have developed; early enteral nutrition has already been highlighted for severe acute pancreatitis, but the therapeutic risks versus benefits need to be studied. AIMS AND OBJECTIVE To compare total ...
متن کاملEnteral nutrition in severe acute pancreatitis.
CONTEXT There is controversy concerning the merits of enteral and parenteral nutrition in the management of patients with severe acute pancreatitis. OBJECTIVE This study was undertaken to evaluate the effect of enteral nutrition versus parenteral nutrition on serum markers of inflammation and outcome in patients with severe acute pancreatitis. SETTING Tertiary care centre in North India. ...
متن کاملMeta-analysis of parenteral nutrition versus enteral nutrition in patients with acute pancreatitis.
OBJECTIVE To compare the safety and clinical outcomes of enteral and parenteral nutrition in patients with acute pancreatitis. DATA SOURCES Medline, Embase, Cochrane controlled trials register, and citation review of relevant primary and review articles. STUDY SELECTION Randomised controlled studies that compared enteral nutrition with parenteral nutrition in patients with acute pancreatiti...
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تاریخ انتشار 2003